Bioethicists teaching and writing about the uses of prenatal genetic testing sometimes use “difficult cases” in which people with a disability want to test and select for the presence of their disability. Such cases challenge our stereotypes but also play into them.

To prepare for potential human infection challenge studies involving SARS-CoV-2, we convened a multidisciplinary working group to address ethical questions regarding whether and how much SAR...

College students from small, medium, and large institutions with either a modified or no honor code were presented with cheating scenarios and asked to rate how dishonest they perceived the behavior to be and the likelihood that they would report it. No main effects were found for institution size or type of honor code. Student–faculty ratio was not correlated with responses to the cheating scenarios. Students from modified honor code schools perceived more severe punishments for cheating and understood the reporting (...) process better than students from non–honor code schools. Implications for modified honor code systems are discussed. (shrink)

In this article, using the recent work by Charles Taylor in A Secular Age as my point of departure, I will argue that Jean-Luc Nancy enables us to think past the competing binary of atheistic and religious experience and allows us to surpass the present narratives of secularism. In A Secular Age, Taylor himself seeks a middle ground between atheism and religion, arguing that it is possible to open ourselves to the cross-pressures of modern existence that find us caught between (...) scientific atheism and a need for spiritual and religious guidance. Here, Taylor finds a way of picturing ourselves within a secular age, remaining faithful to scientific rationalism, but still open to religion and a sense of a higher good. However, as I shall demonstrate, in his thesis Taylor misrepresents the Continental philosophical tradition (particularly Nietzsche and post-structuralism) that has itself sought to understand these cross-pressures of existence. Taking this misrepresentation, and specifically his reductive and colloquial analysis of Nietzsche, Camus, and Derrida, as my point of departure, I provide an alternative manner of thinking through the work of these writers, one that leads to a detailed analysis of Jean-Luc Nancy and his project the deconstruction of Christianity. In this analysis I argue that Nancy provides a manner of thinking that remains open and allows an experience of freedom, without seeking to close that sense of openness with explanation, nor maintaining that sense of openness with a conception of the divine. (shrink)

To address growing concerns about academic integrity, college students (n?=?758) at honor system and non-honor system institutions were presented with eight scenarios to determine the influence of an honor system on their perceptions of and responses to academic dishonesty. Main effects for honor code status emerged. Students from traditional honor system schools considered the behaviors to be more dishonest, and were more likely to respond that they would report the incident when compared to students attending modified and non-honor system institutions. (...) Findings suggest traditional honor systems, with specific rules and regulations in place, are more effective at cultivating academic integrity among students; modified honor systems may not be as effective as previous research suggests. (shrink)

The peer commentaries on our Target Article, “Promoting Ethical Payment in Human Infection Challenge Studies,” offer a number of insights that will help advance the co...

Rare genetic diseases collectively impact millions of individuals in the United States. These patients and their families share many challenges including delayed diagnosis, lack of knowledgeable providers, and limited economic incentives to develop new therapies for small patient groups. As such, rare disease patients and families often must rely on advocacy, including both self-advocacy to access clinical care and public advocacy to advance research. However, these demands raise serious concerns for equity, as both care and research for a given disease (...) can depend on the education, financial resources, and social capital available to the patients in a given community. In this article, we utilize three case examples to illustrate ethical challenges at the intersection of rare diseases, advocacy and justice, including how reliance on advocacy in rare disease may drive unintended consequences for equity. We conclude with a discussion of opportunities for diverse stakeholders to begin to address these challenges. (shrink)

The rapid advances in genomics over the last decade have come to fruition amid intense public discussions of justice in medicine and health care. While much emphasis has been placed on increasing diversity in genomics research participation, an overly narrow focus on recruitment eschews recognition of the disparities in health care that will ultimately shape access to the benefits of genomic medicine. In this essay, we suggest that achieving a just genomics, both now and in the future, requires an explicit (...) ELSI of translation—normative and pragmatic scholarship that embraces the interconnectedness of research and clinical care and centers the obligations of researchers, institutions, and funders to mitigate inequities throughout the translational pipeline. We propose core principles to guide an ELSI of translation and to ensure that this work balances the value of the generalizable knowledge that genomics research generates and the value of the individuals and communities who make this research possible. (shrink)

Newborn bloodspot screening programs are some of the longest running population screening programs internationally. Debate continues regarding the need for parents to give consent to having their child screened. Little attention has been paid to how meanings of consent-related terminology vary among stakeholders and the implications of this for practice. We undertook semi-structured interviews with parents, healthcare professionals and policy decision makers in two Canadian provinces. Conceptions of consent-related terms revolved around seven factors within two broad domains, decision-making and information (...) attainment. Decision-making comprised: parent decision authority; voluntariness; parent engagement with decision-making; and the process of enacting choice. Information ascertainment comprised: professional responsibilities ; parent responsibilities; and the need for discussion and understanding prior to a decision. Our findings indicate that consent-related terms are variously understood, with substantive implications for practice. We suggest that consent procedures should be explained descriptively, regardless of approach, so there are clear indications of what is expected of parents and healthcare professionals. Support systems are required both to meet the educational needs of parents and families and to support healthcare professionals in delivering information in a manner in keeping with parent needs. (shrink)

In this paper, we discuss our approach to developing engaging course content linked to distinct learning outcomes on the topic of academic authorship. Academic authorship is a critical element of research culture and responsible conduct of research (RCR) courses. Drawing on instructional design methods, our online course aims to stimulate critical thinking about ethical authorship practices and to help students develop skills for resolving authorship-related conflicts. The course is scaffolded to facilitate engagement by tying video and podcast-style media, a choice-based (...) interactive simulation, and traditional case study activities, to specific learning objectives. We describe how each instructional technique enhances student engagement and learning for the paired objective, and the benefits of the holistic course design. Finally, we illustrate how RCR instructors can incorporate our materials in full or in part into their own course curricula and encourage others to use our course development approach when designing their own courses. (shrink)

BackgroundDeveloping a comprehensive, reproducible literature search is the basis for a high-quality systematic review (SR). Librarians and information professionals, as expert searchers, can improve the quality of systematic review searches, methodology, and reporting. Likewise, journal editors and authors often seek to improve the quality of published SRs and other evidence syntheses through peer review. Health sciences librarians contribute to systematic review production but little is known about their involvement in peer reviewing SR manuscripts.MethodsThis survey aimed to assess how frequently librarians (...) are asked to peer review systematic review manuscripts and to determine characteristics associated with those invited to review. The survey was distributed to a purposive sample through three health sciences information professional listservs.ResultsThere were 291 complete survey responses. Results indicated that 22% (n = 63) of respondents had been asked by journal editors to peer review systematic review or meta-analysis manuscripts. Of the 78% (n = 228) of respondents who had not already been asked, 54% (n = 122) would peer review, and 41% (n = 93) might peer review. Only 4% (n = 9) would not review a manuscript. Respondents had peer reviewed manuscripts for 38 unique journals and believed they were asked because of their professional expertise. Of respondents who had declined to peer review (32%, n = 20), the most common explanation was “not enough time” (60%, n = 12) followed by “lack of expertise” (50%, n = 10).The vast majority of respondents (95%, n = 40) had “rejected or recommended a revision of a manuscript| after peer review. They based their decision on the “search methodology” (57%, n = 36), “search write-up” (46%, n = 29), or “entire article” (54%, n = 34). Those who selected “other” (37%, n = 23) listed a variety of reasons for rejection, including problems or errors in the PRISMA flow diagram; tables of included, excluded, and ongoing studies; data extraction; reporting; and pooling methods.ConclusionsDespite being experts in conducting literature searches and supporting SR teams through the review process, few librarians have been asked to review SR manuscripts, or even just search strategies; yet many are willing to provide this service. Editors should involve experienced librarians with peer review and we suggest some strategies to consider. (shrink)

William E. Connolly, A World of Becoming Content Type Journal Article Category Book Review Pages 138-141 Authors Alexander C. Karolis, School of Philosophy, Research School of Social Sciences, Australian National University Journal Critical Horizons: A Journal of Philosophy & Social Theory Online ISSN 1568-5160 Print ISSN 1440-9917 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / 2012.

Some scholars have seen in ‘fulminat’ an allusion to Callimachus' βροντν οκ μν, λλ Διc , and that is reasonable enough, since Virgil contrasts the warlike fulminations of Octavian with mocking disparagement of his own very different lifestyle . But it may have escaped attention that Virgil seems to be imitating some lines by another Hellenistic poet, Rhianus ; the parallel has thought-provoking implications.

A novel Protocol Ethics Tool Kit (‘Ethics Tool Kit’) has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women9s Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investigators and sponsors to develop a dedicated Ethics Section within a protocol to improve the consistency and transparency between clinical trial (...) protocols and research ethics committee reviews. It may also streamline ethics review and may facilitate and expedite the review process by anticipating the concerns of ethics committee reviewers. Specific attention was given to issues arising in multinational settings. With the use of this Tool Kit, researchers have the opportunity to address critical research ethics issues proactively, potentially speeding the time and easing the process to final protocol approval. (shrink)

Already an admired senior poet to Virgil in the Eclogues , Varius by the mid-thirties, B.C. had established himself as the leading epic writer of his day . It is a sobering thought that we do not know even the titles of the serious hexameter works which had won him so high a reputation, except for de Morte, quoted four times by Macrobius.

Michael Choniates (c. 1138–c. 1222), a pupil of Eustathius of Thessalonica, who was Greek Orthodox Metropolitan of Athens for some 25 years up to that city's capture by Frankish crusaders ina.d.1205, is best known to classical scholars as the possessor of probably the last complete copy of Callimachus'HecaleandAetia. He had brought with him from Constantinople many books of all kinds, and added to his collection when in Athens. Although an immense task, it would be well worth trying to identify all (...) Michael's classical allusions, as an indication of how much ancient Greek literature was still available just before Constantinople too succumbed to the crusaders. (shrink)

Preface, by F. L. Windolph.--A modern concept of God, by A. H. Compton.--The immortality of man, by J. Maritain.--The idea of God in the mind of man, by M. Royden.--Psychical research and the life beyond death, by H. Hart.--Religion and modern knowledge, by R. Niebuhr.--Immortality in the light of science and philosophy, by W. E. Hocking.--"To whom shall ye liken God?" By C. E. Park.--Man's destiny in eternity, by W. L. Sperry.--The idea of God as affected by modern knowledge, by (...) F. S. C. Northrop. (shrink)

Moti Mizrahi provides experimental evidence according to which subjects judge that a person ought to ? even when she cannot ?. He takes his results to constitute a falsification of the alleged intuitiveness of the ‘Ought Implies Can’ principle. We point out that in the light of the fact that (a) ‘ought’ is multiply ambiguous, that (b) only a restricted set of readings of ‘ought’ will be relevant to the principle, and that (c) he did not instruct his subjects appropriately (...) – or otherwise ensure that in their ‘ought’ judgements they applied the relevant concept(s) – Mizrahi’s conclusions appear premature. We suggest two ways in which the experimental design could be adjusted or supplemented. First, Mizrahi could instruct (or prime) subjects to read the ‘ought’ question in a particular way. Second, he could complement his experiment by asking follow-up questions aimed at uncovering the implications for blame of subjects’ judgements. Once these adjustments are applied, an experiment with a similar outcome would be more significant. (shrink)

Racism is a pervasive issue in patient care and a key social determinant of health. Clinical ethicists, like others involved in patient care, have a duty to recognize and respond to racism on both individual and systems-wide levels to improve patient care. Doing so can be challenging and, like other skills in ethics consultation, may benefit from specialized training, standardized tools and approaches, and practice. Learning from existing frameworks and tools, as well as building new ones, can help guide clinical (...) ethicists to systematically approach racism as it affects clinical cases. Here, we propose an expansion of the commonly used four-box method to clinical ethics consultation, where racism is considered as a potential factor in each of the four boxes. We apply this method to two clinical cases to highlight ethically salient information that might be missed using the standard formulation of the four boxes but captured with the expanded version. We argue that this expansion of an existing clinical ethics consultation tool is ethically justified insofar as it (a) creates a more just approach, (b) supports individual consultants and services, and (c) facilitates communication in contexts where racism impinges on effecting good patient care. (shrink)

The Latin text is established from the first edition of the Epistola and Hollis' edition. Since the author regards Popple's English translation, which is here edited and reprinted en regard, as having been supervised and approved by Locke himself, it is taken to be as authoritative as the Latin and accordingly is used in establishing the Latin text. The translation is established from its first and second editions. Montuori has not always indicated his departures from Locke's spelling and punctuation, (...) although the pagination of the collated texts is indicated in the margin. Locke's second and third Letters Concerning Toleration are not reprinted here.—H. C. (shrink)

In Hollis’ paradox, A and B each chose a positive integer and whisper their number to C. C then informs them, jointly, that they have chosen different numbers and, moreover, that neither of them are able to work out who has the greatest number. A then reasons as follows: B cannot have 1, otherwise he would know that my number is greater, and by the same reasoning B knows that I don’t have 1. But then B also cannot have (...) 2, otherwise he would know that my number is greater (since he knows I don’t have 1). This line of reasoning can be repeated indefinitely, effectively forming an inductive proof, ruling out any number – an apparent paradox. In this paper we formalise Hollis’ paradox using public announcement logic, and argue that the root cause of the paradox is the wrongful assumption that A and B assume that C’s announcement necessarily is successful. This resolves the paradox without assuming that C can be untruthful, or that A and B are not perfect reasoners, like other solutions do. There are similarities to the surprise examination paradox. In addition to a semantic analysis in the tradition of epistemic logic, we provide a syntactic one, deriving conclusions from a set of premises describing the initial situation – more in the spirit of the literature on Hollis’ paradox. The latter allows us to pinpoint which assumptions are actually necessary for the conclusions resolving the paradox. (shrink)

Bambrough, R. Essay on man.--Quinton, A. Has man an essence?--Warnock, G. J. Kant and anthropology.--Honderich, T. On inequality and violence, and the differences we make between them.--Cherry, C. Agreement, objectivity and the sentiment of humanity in morals.--Gregory, I. Psycho-analysis, human nature and human conduct.--Gosling, J. The natural supremacy of conscience.--Scruton, R. Reason and happiness.--Wollheim, R. Needs, desires, and moral turpitude.--Hollis, M. My role and its duties.--Watkins, J. Three views concerning human freedom.--Letwin, S. R. Nature, history, and morality.--Passmore, J. Attitudes (...) to nature.--Benson, J. Hog in sloth, fox in stealth: man and beast in moral thinking.--Hare, R. Contrasting methods of environmental planning.--Self, P. Techniques and values in policy decisions. (shrink)

William C. Gentry was both an academic philosopher, perfectly willing to engage in the philosophical 'conversations' of the written word and, more importantly, a true philosopher, in the Platonic and Socratic style. Engaging with those around him in discourse, in live conversations, which are the vehicle of actual philosophical inquiry and discovery. These essays are the product of those conversations. Gentry's thoughts consisted of investigations into the deepest and most profound questions of human nature, ethics, and knowledge. This volume is (...) a tribute both to his role as a teacher and philosopher. As a teacher, friend, and colleague, Gentry was the epitome of the philosopher: questioning, exploring, critiquing, discovering. (shrink)

From whence spring the sparks of creativity? It is to this very question that the field of depth psychology--especially that of C.G. Jung and his intellectual descendants--has much to contribute. Just as the Muses were the offspring of Mnemosyne, the goddess of memory, our memories are the ancestors of our creativity that finds its multifaceted expression in the written word, image, theater, dance, and music. The Unconscious Roots of Creativity seeks to push the investigation into that domain of memory that (...) is beyond our conscious reach. With articles from 16 contributors, the "red thread" running through each of the offerings in this volume is that, whatever its ultimate expression, the creative impulse has its roots deep in the psyche. Edited By Kathryn Madden, Leonard Cruz and Steven Buser with articles by Linda Carter, Anna Maria Costantino, Carol Thayer Cox, Leonard Cruz, Lisa Raye Garlock, James Hollis, Naomi Ruth Lowinsky, Ian Livingston, Kathryn Madden, Jordan S. Potash, Susan Rowland, Murray Stein, Ann Ulanov, Tjeu van den Berk, Robin van Loben Sels, and Heidi S. Volf. (shrink)

The fact that the mystical experience is a repetitive phenomenon in different social, cultural and religious structures in different periods and has a mysterious element in it has caused that mysticism has taken its place among the basic subjects of the field since the first periods of psychology of religion. One of the sections of The Varieties of Religious Experience, which is regarded as the main source of the area, is mysticism. In general, "mystical experience" is considered as a subcategory (...) of "religious experience", which is a wider area. For this reason, it also carries the characteristics of religious experience. Due to these common features, it can be seen that they are used in place of each other in the literature. If the religious experience is defined as the experience of the individual at the time of encounter with the sacred, such experience can be obtained in two ways. In the “religion-based mystical experience”, which is the first way, institutional or established religious thoughts and understandings and holly writings are influential. The second way, “non-religious or natural mystical experience”, can be said to be spiritual quests that individual needs play an important role in them are effective. Personality is used as one of the basic variables in social and health sciences in general, and in psychology because it is among the main subjects in particular. The common emphasis of research on personality is that the phenomenon is extremely complicated. Despite its widespread use, the abstraction of the concept has been influenced by the diversity of the researchers' perspectives and this has led to a lack of clear consensus on the definition. However, in order to investigate the phenomenon in recent periods, dimensional approaches that their basic assumption is personality can be categorized under certain factors have begun to be preferred. In this study, HEXACO was used, because it was thought that it could make a more detailed measurement of personality. The sample of this study is composed of 345 students studying at Erciyes University Theology Faculty in 2017-2018 academic year. When looked at the gender distribution of the sample, the rate of male students was 21.2% (n=73); and the rate of female students was 78.8% (n=272). This reflects the current situation in the faculty. The average age was 21,13 (sd=1,761). The age range is 18-26. Class distribution was 23,5% (n = 81) in Preparatory class; 15.4% (n = 53) in first-grade; 19.4% (n = 67) in second-grade; 18.3% (n=63) in third grade (n = 63); and 23.5% (n = 81) in the fourth grade. It has been noted that distributions are homogeneous in terms of class variables. The "Mystical Experience Scale" which is developed by Ralph W. Hood to measure the criteria which are offered by Walter T. Stace and which must be in the mystical experience has been used in determining the tendency of mystical experience. Hood et al. have reported reasonable reliabilities for subscales based on 3-factor solution. Alpha coefficients of the original scale were ,76, ,69, and ,76 for the extrovertive mysticism, introvertive mysticism and religious interpretation respectively. The adaptation of the scale to Turkish culture and the validity and reliability study were carried out by Mehmet Süheyl Unal as a graduate thesis and it was stated that the Alpha coefficient was ,89. In this study, the Cronbach Alpha reliability coefficient of scale is ,91. HEXACO, developed by Lee and Ashton, was used to determine personality traits. The scale was adapted to Turkish by Wasti, Lee, Ashton and Somer. The scale consists of Honesty-humility (H), Emotionality (E), eXtraversion (X), Agreeableness (A), Conscientiousness (C), and Openness to experience (O) factors. Pearson Moments Multiplication Correlation Analysis was performed to determine if there is a relationship between mystical experience tendencies and personality traits when the data were analyzed in accordance with the aim of the study. Later, it was tried to determine the power of explaining the variables with Multiple Linear Regression Analysis. In addition, One-way ANOVA was used to determine whether there was any relationship between significance levels. Moreover, descriptive statistics of relevant variables are included in the study. Findings show that participants have the highest average to Positive Affect (m=3,69; sd.=,77) and the lowest average to Temporal/Spatial Quality (m=2,94; sd.=,89) factor in terms of mystical experience. Additively, they obtained close values in Ego Quality, Noetic Quality and Ineffability factors. When the students were evaluated in terms of gender, it was seen that there was a difference in level of significance only in terms of Unifying Quality (t=1,770; p=,028). ANOVA analysis was carried out to determine whether there was any variation in class variable. As a result of this analysis, it is seen that all of the factors are significantly differentiated in terms of class variable. From the standing point of class variable, it is seen that the first grades differed negatively compared to the other classes. According to the data, the scores on the mystical experience scale for preparation and first grade are high while the averages for the next grade are falling. There is no difference on level of significance between age and mystical experience factors, the last independent variable. When looked at the correlations among mystical experience factors, it is understood that all of the factors are in a meaningful relationship with each other. The highest correlation is between Religious Quality and Ineffability (r=,661); the lowest correlation is between the Unifying Quality and the Temporal/Spatial Quality (r=,346). Among the six factors of HEXACO that have been developed to determine the personality traits, the students have the highest average on Humility-Honesty (m=3,76; sd.=,55); the lowest average on eXtraversion (m=3,04; sd.=0,65). In terms of gender, there is a statistically significant difference in factors of Humility-Honesty (t=,606; p=,004), Emotionality (t=,334; p=,000), and Constientiousness (t=,022; p=,033). There is no significant difference between class and age variables and personality traits. According to Linear Regression analysis, Agreeableness, Constientiousness and Openness to Experience factors of personality traits are predictive of mystical experience in a significant level statistically. Personality dimensions that are most related to mystical experience as a result of analysis are Conscientiousness and Openness to Experience. When the mystical experience is compared with the personality traits, it is concluded that Openness to Experience factor is related to all the factors of the mystical experience except for the Ineffability. Although the relationship is regarded as weak in terms of correlation, it is an important finding that there are positive relations in between. In other words, as personality traits evolve, the mystical experience level also increases. The lack of a similar work in the literature in this respect removes the possibility of making comparisons. (shrink)

Contrary to Austin's view that a fanciful use of language, like poetry, does not carry illocutionary acts and is therefore "parasitic," the author follows through C. Carroll Hollis' work in showing that poets use illocutionary acts in a certain way that may be studied meaningfully, thereby making a speech act a form of literary criticism. She does this by applying the categories of speech acts in her study of some of the love poems of a Filipino poet, Dr. Elynia (...) Mabanglo. In the end, she shows that even though the poet does not use language in what Austin refers to as the "normal" sense, the mimetic character of certain poetry does allow the use and fulfillment of illocutionary acts. (shrink)

Higher-order thought theories maintain that consciousness involves the having of higher-order thoughts about mental states. In response to these theories of consciousness, an attempt is often made to illustrate that nonhuman animals possess said consciousness, overlooking an alarming consequence: attributing higher-order thought to nonhuman animals might entail that they should be held morally accountable for their actions. I argue that moral responsibility requires more than higher-order thought: moral agency requires a specific higher-order thought which concerns a belief about the rightness (...) or wrongness of affecting another’s mental states. This “moral thought” about the rightness or wrongness is not yet demonstrated in even the most intelligent nonhuman animals, thus we should suspend our judgments about the “rightness” or “wrongness” of their actions while further questioning the recent insistence on developing an animal morality. (shrink)

C A Wringe; Pupils’ Rights, Journal of Philosophy of Education, Volume 7, Issue 1, 30 May 2006, Pages 103–115, https://doi.org/10.1111/j.1467-9752.1973.tb00475.

In this paper, we provide a logical formalization of the emotion triggering process and of its relationship with mental attitudes, as described in Ortony, Clore, and Collins’s theory. We argue that modal logics are particularly adapted to represent agents’ mental attitudes and to reason about them, and use a specific modal logic that we call Logic of Emotions in order to provide logical definitions of all but two of their 22 emotions. While these definitions may be subject to debate, we (...) show that they allow to reason about emotions and to draw interesting conclusions from the theory. (shrink)

The lateralized ERP N2pc component has been shown to be an effective marker of attentional object selection when elicited in a visual search task, specifically reflecting the selection of a target item among distractors. Moreover, when targets are known in advance, the visual search process is guided by representations of target features held in working memory at the time of search, thus guiding attention to objects with target-matching features. Previous studies have shown that manipulating working memory availability via concurrent tasks (...) or within task manipulations influences visual search performance and the N2pc. Other studies have indicated that visual vs. spatial working memory manipulations have differential contributions to visual search. To investigate this the current study assesses participants' visual and spatial working memory ability independent of the visual search task to determine whether such individual differences in working memory affect task performance and the N2pc. Participants completed a visual search task to elicit the N2pc and separate visual working memory and spatial working memory assessments. Greater SPWM, but not VWM, ability is correlated with and predicts higher visual search accuracy and greater N2pc amplitudes. Neither VWM nor SPWM was related to N2pc latency. These results provide additional support to prior behavioral and neural visual search findings that spatial WM availability, whether as an ability of the participant's processing system or based on task demands, plays an important role in efficient visual search. (shrink)